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C4 Extreme Energy Cherry Limeade

Backed by 24 studies

Overall grade based on research across 8 ingredients.

B
74out of 100Grade B
Research evidence score

Weighed against 24 published studies · led by Vitamin C

How the ingredients work together

Known interactions from published nutrition research — separate from the evidence grade.

55 of 5 nutrients at a meaningful dose (≥20% Daily Value).
B12 + FolateWork together

B12 and folate work in the same methylation cycle; supplementing both supports homocysteine metabolism better than either alone.

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Ingredient breakdown

A
Vitamin CSupports immune function and antioxidant defense
Research: Established essential nutrientDaily Value: 278%Dose: 250 mgEvidence strength: Established nutrient — this product provides a meaningful dose
C
NiacinSupports cholesterol metabolism and cellular energy
Research: Established essential nutrientDaily Value: 375%Dose: 60 mgEvidence strength: Established nutrient — this product provides a meaningful dose
A
Vitamin B6Supports energy metabolism and neurotransmitter synthesis
Research: Established essential nutrientDaily Value: 59%Dose: 1 mgEvidence strength: Established nutrient — this product provides a meaningful dose
A
FolateSupports DNA synthesis and neural tube development
Research: Established essential nutrientDaily Value: 125%Dose: 500 mcgEvidence strength: Established nutrient — this product provides a meaningful dose
A
Vitamin B12Supports energy and nerve function
Research: Established essential nutrientDaily Value: 2917%Dose: 70 mcgEvidence strength: Established nutrient — this product provides a meaningful dose
D
Beta-alanineImproves exercise endurance and reduces fatigue
Research direction: Leans unsupportiveEvidence: 19 studiesDose: 3.2 GramEvidence strength: Weak - research is split or limited
Creatine NitrateSupports health outcomes
Research direction: No studies foundEvidence: 0 studiesDose: 1 GramEvidence strength: Not enough research yet - no studies found for this specific claim
C
Arginine Alpha KetoglutarateSupports health outcomes
Research direction: InconclusiveEvidence: 5 studiesDose: 1 GramEvidence strength: Moderate - supportive but mixed

This summary describes only the ingredients and the research behind them — it is not a judgment of the product or its marketing. Grades reflect the weight of published evidence cross-referenced against 350M+ research papers. How we grade →

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